In fact, the nitrile functional group is an integral component of numerous pharmaceutical drugs including cimetidine (Tagamet), verapamil (Isoptin), and citalopram (celexa). Generally, nitriles do not display high toxicity. These compounds are usually called nitriles although they are sometimes called organic cyanides.
Many thousands of organic compounds contain the CN group. In fact, it is administered orally as an antidote to poisoning by thallium and Caesium-137. On the other hand, Prussian blue, with an approximate formula Fe 7(CN) 18 is the blue of blue prints and does not release cyanide ions easily. Some compounds readily release HCN or the cyanide ion for example such as trimethylsilyl cyanide (CH 3) 3SiCN upon contact with water and cyanoacrylates upon pyrolysis.
The oral median lethal dose, or LD 50 of potassium cyanide is about 5–10 milligrams per kilogram of body weight for rats, mice, and rabbits. The most dangerous cyanides are hydrogen cyanide (HCN) and salts derived from it, such as potassium cyanide (KCN) and sodium cyanide (NaCN), among others. Many cyanide-containing compounds are highly toxic, but many are not.
0 kommentar(er)
